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McHutchinson JG, Gordon SC, Schiff ER, Shiffman ML, Lee WM, Rustgi VK, Goodman ZD, Ling MH, Cort S, Albrecht JK, for The Hepatitis Interventional Therapy Group: Interferon alfa-2b alone or in combination with ribavirin as initial treatment for chronic hepatitis C

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Mitochondrial ROS and lipid peroxidation increase under chronic stress without immediate cell death

This is not a medication failureit is a mismatch between the drug and the individual's biological hardware

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