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Prescription and administration: Once B12 deficiency is confirmed, GPs prescribe hydroxocobalamin injections according to standardised protocols: Standard loading regimen: 1mg intramuscularly three times weekly for two weeks Neurological involvement: 1mg intramuscularly on alternate days until no further improvement Maintenance therapy: 1mg every three months for life in pernicious anaemia or malabsorption conditions (or every two months if there was neurological involvement) Injections are typically administered by practice nurses at GP surgeries

A 2025 pilot IV study (1020mg, n=2) showed no adverse effects on biomarkers

[61] was 7.7 years

2017;97(Pt B):11926

BPC157 components of Wolverine Blend have been studied for mucosal and gut healing in preclinical models, but Wolverine protocols focused on gut health remain experimental and must be individualized by a provider