Cell 148:12931307 Clayton TA, Lindon JC, Cloarec O, Antti H, Charuel C, Hanton G, Provost JP, Le Net JL, Baker D, Walley RJ, Everett JR, Nicholson JK (2006) Pharmaco-metabonomic phenotyping and personalized drug treatment
Journal of Clinical Peptide Research, 15 (3), 45-58
A recent investigation revealed that the expression of VRK2 was upregulated in response to ROS signals, while the link between VRK2 and metabolic rewiring remains obscure [18].In this study, we tried to explore the effects of VRK2 on the rewiring of metabolic networks and identify metabolic vulnerabilities resulting from VRK2-driven metabolic reprogramming
The team established a predictive model for PCOS based on a combination of five bile acids (AUC = 0.86), underscoring bile acids as early warning biomarkers for metabolic dysfunction (80)
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