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Even if a molecule is affected by irradiation, and thus undergoes the process of direct photodegradation, it does not mean that the contamination problem is solvedproducts of photochemical reactions can be more toxic than parent compounds, e.g., irradiation of naproxen generates possibly genotoxic derivatives (Isidori et al

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there is also data to suggest that slower titration regimens (employed in GLP-1-insulin combo therapies), may reduce rates of nausea and vomiting further