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doi: 10.1038/s41551-019-0397-0 143 DellAttiFAbreuHMalfaPRaineriDCappellanoGChiocchettiA

This longer duration of action allows for less frequent use in research protocols, reducing the number of interventions needed and minimizing stress on research subjects

d , Autoantibody-induced mechanical hypersensitivity and joint pain only showed in Cas9 mice intrathecally received AAV-PHP.s-Cre but not CRISPR-gRNA-Ifnar1 AAV virus (n = 6/group)

Funding This study was supported by the Delegation for Clinical Research of the University Medical Center of Nantes (CHU de Nantes)