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By targeting appetite regulation, glucose control, and energy balance, cagrilintide may represent an important step forward in managing obesity, type 2 diabetes, and related metabolic conditions ( 1, 3 )

Accordingly, macrophage depletion via small molecule inhibition of the pro-survival receptor CSF1R is sufficient to reduce OL loss and demyelination in the cuprizone model, and administration of the ligand CSF1 is sufficient to cause demyelination 172

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Several drugs targeting autism are under study (Table 3) and clinical trials (Table 4)