In people with type 2 diabetes, both the secretion and action are deficient of GLP-1
JACC Heart Fail 11:10001010 Hollstein T, Schlicht K, Krause L et al (2021) Effect of various weight loss interventions on serum NT-proBNP concentration in severe obese subjects without clinical manifest heart failure
Primary outcomes included changes in body weight, BMI, waist circumference, fasting glucose, HOMA-IR, androgen levels, and sex hormone-binding globulin (SHBG)
Semaglutide is approved for type 2 diabetes , and higher doses are marketed under a different name for weight management
These include: Eating more protein: Protein helps build more muscle mass, which helps you burn more calories