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Metabolic pathways: B12 is a cofactor in two critical reactions: Methylmalonyl-CoA mutase: Converts methylmalonyl CoA (from odd-chain fatty acids and some amino acids) into succinyl-CoA, which enters the Krebs (TCA) cycle to make ATP (cellular energy)

The authors thank all participants and their families

Vesvoranan O, Liu BS, Zheng Y, Wagner WL, Sutlive J, Chen Z, et al

Clinical data show that GLP-1 users usually regain weight without continued use, though people who lose more at first keep more off long-term (ending 12% lighter)

Ozempic, Wegovy and other weight loss drugs mimic the GLP-1 hormone to slow digestion and signal the brain that its full