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In addition to HSCs, in an injured liver, hepatocytes and bile duct cells can also transform into fibroblasts via the process of epithelialmesenchymal transition (EMT), and excessive extracellular matrix (ECM) deposition by fibroblasts contributes to liver fibrosis

Glutathione deficiency and oxidative stress have been implicated in the pathogenesis of neurological diseases such as Parkinson's disease, Alzheimer's disease, and multiple sclerosis

Tentori, L

Through this intracellular coupling, astrocytes supply neurons with cysteine or cysteinyl-glycine derived from exported GSH, thereby supporting neuronal GSH synthesis and resistance to damaging, redox-driven processes ( When GSH levels are chronically low, immune cells within the CNS shift to a damage-oriented phenotype

The information provided relates to patient-specific compounding