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One of it is the chronic inflammation that is caused due to autoimmune diseases like celiac disease, rheumatoid arthritis, and the like

The role of ER stress and UPR in NDDs The UPR is a critical cellular mechanism activated in response to the accumulation of misfolded or unfolded proteins in the ER

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Some anti-diabetic drugs can interfere with intracellular metabolic regulation, for example, through activation of AMPK or inhibition of glucose uptake, favoring TC cell death and also reducing its aggressiveness

This article presents a clinical report from the first 8 SLE patients treated with anti-CD19 CAR-T cells in Erlangen