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As an important regulator of Wnt transduction in the canonical signaling pathway in tumours, Dickkopf-related protein 3 (DKK3) negatively regulates aerobic glycolysis [HK2, HIF-1, GLUT-1, LDHA and 3-phosphoinositide-dependent protein kinase-1 (PDK-1)] in BxPC-3 cells
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Thus, the aim of this study was to evaluate the efficacy of probiotics as a therapeutic strategy in the management of obesity and overweight. 7 Additionally, a clinical trial tested pre- and probiotics in 45 obese subjects
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