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persistent severe abdominal pain is a stop-and-evaluate signal

They can also be influenced by diet and environmental factors which means, thankfully, there are ways to treat MTHFR gene mutations

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Pay close attention to: Inclusion and exclusion criteria Location (some trials require in-person visits) Frequency of check ins Study design, like whether the study is randomized and placebo-controlled (a placebo-controlled trial means not everyone receives the medication, which is an important consideration) Study duration (if youre in the placebo group, this is how long without treatment, too!) For instance, some retatrutide clinical trials are only enrolling people with obesity, which means you must be above a certain BMI to qualify