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Peptides are fragile molecules that can degrade, aggregate, or lose their three-dimensional structure when exposed to pH fluctuations, temperature changes, light, or even the simple act of sitting in a vial for weeks at a time

The rationale is that the two molecules are not equipotent at nominally similar doses, and the titration schedule for tirzepatide requires a fresh start to minimize GI risk

Heres how to work through it systematically

Retinopathy worsening most commonly appears within the first three to six months of treatment, coinciding with rapid blood sugar improvement

Ikeji Last reviewed: 07 Aug 2024 Semaglutide is the active ingredient found in the weight loss injection Wegovy