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Visible results are usually seen within six to eight weeks after treatment

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Beetroot is a rich source of phytochemical compounds (Figure 1), that includes ascorbic acid, carotenoids, phenolic acids and flavonoids [2,20,21]

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To date, few radiosensitising drugs have been approved for use clinically ( in vitro and ex vivo models of oesophageal adenocarcinoma ( Metformin is a clinically approved drug used for the management of type II diabetes ( This study demonstrates, through real-time live cell metabolic profiling and transcriptomic profiling, that metformin significantly alters energy metabolism in both in vitro and ex vivo models of rectal adenocarcinoma and importantly, radiosensitises radioresistant rectal cancer cells to clinically-relevant doses of X-ray radiation