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Jessica Duncan, testified before the FDAs Pharmacy Compounding Advisory Committee (PCAC) in Washington, D.C

recently reported a small experience of combination therapy of ibrutinib with ruxolitinib for steroid refractory cGvHD in two pediatric patients and found this combination to be well tolerated with no significant adverse events for neither patient had to discontinue these drugs (65)

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These medications have shown promise in improving cognitive function and offering neuroprotective effects, especially in patients with metabolic disorders like type 2 diabetes