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Although the milestone of the treatment of obesity in PWS is the prevention that could occur thanks to growth hormone (GH) therapy and lifestyle interventions started in childhood [32], nutritional interventions along with the use of current antiobesity drugs provide evidence to be effective in adult subjects with obesity [44]
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They found that Humanin modestly but consistently elevated ATP production in a dose-dependent manner, suggesting enhanced fatty acid oxidation alongside the suppression of lipid synthesis [1]
Carr J, Mackie RM
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