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Kisspeptin-10 acts upstream at the hypothalamic level, stimulating GnRH release which then drives LH and FSH secretion from the pituitary

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Interestingly, in an in vitro study, it was demonstrated that a recombinant circumsporozoite protein, the main surface protein of the malaria parasites sporozoite stage, inhibited the proliferation of the human colon cancer cell line, SW480 in a dose-dependent manner