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this was found to have a significant effect on progression to requiring treatment in early PD

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It is suggested that prompt correction of deficiency should be done within 6 to 12 months of cognitive impairment in order to obtain maximum response.57 Nevertheless, continuous replacement therapy may still help to prevent symptoms from deteriorating

[5] [6] The British Association of Dermatologists and NHS provide patient-facing guidance on hair loss assessment and when to seek care