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Ipamorelin and IGF-1 Research Research comparing Ipamorelin to GHRH-receptor agonists confirmed that elevated GH following GHS-R activation stimulates downstream IGF-1 production in hepatic and peripheral tissues, with studies examining differences in secretion kinetics, peak amplitude, and duration of GH and IGF-1 signalling between receptor subtype classes

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[13] [14] [15] [26] It is sold as a generic drug by several drug companies in the Indian and Canadian markets, and worldwide by its originator, Novo Nordisk, under the brand names Ozempic and Rybelsus for diabetes