The sensation of feeling cold appears to be an indirect consequence of the metabolic and body composition changes induced by the medication, rather than a direct drug effect on temperature regulation centres in the hypothalamus
Semaglutide vs tirzepatide how each works, how they differ, and whether tirzepatide is really better for weight loss
1 A review article of multiple randomized controlled trials reports an average weight loss of around 16% among users, with some losing as much as 17.4%
But what youre finding even with GLP-1s is that if there is a psychological component to it, that its more emotional eating, stress, as opposed to in response to the sight or taste of food, its not going to be as effective, and youre more likely to go back to the same behaviors after going off of them
Fatigue management through timing Tirzepatide-related GLP-1 fatigue typically follows a predictable pattern