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Description

Restless Legs Syndrome (RLS)

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Activation of Y2R increases phosphodiesterase 3B (PDE3B) activity, lowering cAMP levels and inhibiting PKA, which reduces the phosphorylation and activity of hormone-sensitive lipase (HSL) and adipose triglyceride lipase (ATGL) (131, 132)

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Deogracias JJ, Johnson LL, Meyer-Bahlburg HF, Kessler SJ, Schober JM, Zucker KJ

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