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Vitamin B12 injections have also been shown to have potent anti-inflammatory properties, helping to increase energy and reduce fatigue.

No significant systemic copper elevation has been reported from topical application in healthy adults

For instance, patients with Wolfram Syndrome (WS) have rare autosomal recessive mutations in their WFS1 gene that give rise to multiple complications, such as juvenile-onset diabetes, optic atrophy, and deafness (185)

doi: 10.1016/s1568-9972(03)00006-5 45 ShiTTXinZHuaLZhaoRXYangYLWangHet al

Photothermal performance of a novel carbon dot and its conjugate with disulfiram for prostate cancer PC3 cell therapy