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No PT-141s MC1R binding affinity is 50-fold lower than its MC4R affinity, meaning the dose required to produce melanogenesis would far exceed the dose that causes intolerable MC4R-mediated side effects like nausea and blood pressure elevation

P.YuH.SuW.et al (2019a)

Mechanisms of Action and Potential Benefits One of the most intriguing features of Dihexa is its suspected role in promoting synaptogenesis the formation of new synaptic connections in the brain

[DOI] [PMC free article] [PubMed] [Google Scholar] 268.Surette ME

This presentation keeps the research compound consistent batch to batch and simplifies inventory for ongoing laboratory projects