Studies have found it associated with significant weight loss when taken regularly by overweight or obese individuals, who attempted an exercise program to shave excess pounds for over two years
It works through several complementary pathways: Appetite regulation : Wegovy acts on receptors in the brain's appetite centres (particularly the hypothalamus), reducing hunger signals and increasing feelings of fullness after meals [2] Gastric emptying : The medication slows the rate at which food leaves your stomach, prolonging satiety and reducing the desire to eat between meals [2] Blood glucose control : It enhances insulin secretion when blood glucose levels are elevated and suppresses inappropriate glucagon release, which can indirectly support weight management [2] Once injected subcutaneously, semaglutide is absorbed gradually into the bloodstream
Middeldorp ME, Pathak RK, Meredith M, Mehta AB, Elliott AD, Mahajan R, Twomey D, Gallagher C, Hendriks JML, Linz D, McEvoy RD, Abhayaratna WP, Kalman JM, Lau DH, Sanders P
The chart matters
Semaglutide requires weekly injection