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The analysis of variance (ANOVA, if normally distributed) or Kruskal-Wallis test (if not normally distributed) was used for multiple group comparisons of continuous variables and a Chi-square test was used for categorical variables

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provided clinical evidence indicating that synbiotic intervention is correlated with attenuated tissue damage and favorable shifts in mucosa-associated microbiota, reinforcing the therapeutic potential of synbiotics in rectal cancer patients undergoing radiotherapy 221

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