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Besides treating pellagra, NAM has a potential for clinical use in the prevention and treatment of various diseases, such as rosacea, acne [149], and hyperphosphatemia [150]

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Similarly, Lincoff et al59 conducted an RCT enrolling 17,604 patients aged 45 years or older with pre-existing cardiovascular disease and a BMI of 27 or higher but without a history of diabetes

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