In addition to its role in insulin regulation, GLP-1 also has the added benefit of reducing the secretion of another hormone, glucagon, produced by the pancreas
Rotating injection sites between the abdomen, thigh, and upper arm can help reduce the frequency and severity of these local reactions
After reviewing the available evidence from non-clinical studies, clinical trials, post-marketing surveillance data, and the available studies, the PRAC considers that no update to the product information is warranted, said the EMA in a statement
B12 deficiency is a documented concern with long-term GLP-1 use because these medications slow gastric emptying, which can reduce B12 absorption from food
Similar to semaglutide, tirzepatide is a weight loss medication that is injected once weekly under a soft portion of the skin and can be taken either with or without food