The vascular endothelium modulates muscle perfusion through NOmediated vasodilation, whereas skeletal muscle subsequently secretes myokines such as interleukin-6 (IL-6), irisin, and vascular endothelial growth factor (VEGF), which influence endothelial cell activity, angiogenesis, and vascular remodeling (16, 17)
Classical enzymes controlled by NRF2, such as SOD, CAT, and heme oxygenase-1 (HO-1), are localized in various organelles and subcellular locations, where they actively scavenge ROS and neutralize electrophiles (Cuadrado et al
Effects of weight loss interventions for adults who are obese on mortality, cardiovascular disease, and cancer: systematic review and meta-analysis
[Abstract]2022 Sep:104:154337
Closely related to blueberry, bilberry is rich in polyphenols and anthocyanins