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Type-2 inflammatory responses can stimulate B cell proliferation to produce antibodies, mediate humoral immunity, participate in barrier immunity at mucosal surfaces, and play a part in counteracting parasitic infections and allergic diseases ( However, in contradiction to previous evidence, Arifuzzaman and colleagues showed that inulin increased systemic levels of bile acids (particularly cholic acid), which led to an increased IL-33 level via activation of the farnesoid X receptor (FXR) pathway

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For example, clinical data indicated that only about 0.6% of patients on a 0.5 mg dose and 0.2% in certain placebo-controlled trials experienced these reactions

It is frequently utilized in studies examining cellular signaling and tissue response mechanisms