Unfortunately, sometimes, boards like this have to make hard decisions, board member Verner Tepe added during the discussion, saying not approving the removal of these drugs from the employee insurance plans would mean the annual budget is no longer balanced
(289) conducted a meta-analysis of 23 RCTs comprising 931 hemodialysis patients, demonstrating that probiotic/prebiotic/synbiotic interventions significantly reduced plasma p-cresyl sulfate (SMD = 0.38, 95% CI: 0.61 to 0.15), endotoxin (SMD = 0.58), CRP (SMD = 0.61), and IL-6 (SMD = 0.92) [Evidence quality: Moderate - significant heterogeneity in intervention protocols]
Some people may notice mild digestive symptoms, such as bloating, gas or constipation, especially during the initial adjustment phase, though these should resolve within two weeks
Research also discusses effects on growth-factor signaling and collagen organization, which are relevant to connective tissue remodeling
And the signal is strong enough to warrant serious research investment