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AXT showed various effects on HT22 cells, including attenuating mitochondrial dysfunction by regulating the Akt/glycogen synthase kinase (GSK)-3 signaling pathway

Individuals with a history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 should avoid GLP-1 receptor agonists

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Women experiencing new vasomotor symptoms should discuss whether hormonal evaluation is appropriate, particularly if symptoms are severe or atypical for their menopausal status

According to the Zepbound label, the most frequent include nausea (24-29%), diarrhea (18-24%), vomiting (8-10%), and constipation (16-17%)