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doi: 10.1210/jcem.86.10.7912

Administration schedule: Once or multiple times daily based on experimental design

Patients were to be randomized to 1200 mg, 450 mg, or placebo, administered intravenously daily for 3 days followed by weekly for 4 weeks

But delayed rashes tend to appear an average of seven or eight days after injection, and initial trials werent designed to pick up on all symptoms that showed up that late, Blumenthal says, likely because they weren't expecting them