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3,4 Indirect Effects of GLP-1RAs The evidence points to the indirect effects of weight loss and systemic metabolic improvement as being the cornerstones of GLP-1RA efficacy in HF

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If folate deficiency is suspected, it is reasonable to give oral folic acid (0.4 1 mg/day) without doing laboratory investigation for deficiency at least until the hemoglobin and mean corpuscular volume normalizes (or longer if the underlying cause cannot be eliminated)