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Since BSO treatment appears to be critical for FAC-dependent cell death (Figure 1), it can be assumed that mitochondrial LPO is not sufficient for ferroptosis

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Beharier O, Tyurin VA, Goff JP, Guerrero-Santoro J, Kajiwara K, Chu T, Tyurina YY, St Croix CM, Wallace CT, Parry S, Parks WT, Kagan VE, Sadovsky Y (2020) PLA2G6 guards placental trophoblasts against ferroptotic injury