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Beneficial effects of growth hormone treatment in GH-deficient adults

In the ISO-induced male mouse model of stress cardiomyopathy, ISO triggers NLRP3 inflammasome activation via NOX4-dependent mitochondrial ROS generation, up-regulates downstream inflammatory cytokines including IL-6 and TNF-, and promotes recruitment of CD68 + CD11b + macrophages into the myocardium (128)

It was an observational study, demonstrating associations rather than causal links

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This is especially relevant for a supplement sourced from bovine connective tissue, where heavy-metal testing provides meaningful assurance of purity