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Statements Author contributions Y-qM: conceptualization, methodology, software, investigation, and writingoriginal draft

Motor cortex is isolated from P3 pups of WT-eGFP and and prpTDP-43 A315T -UeGFP mice, and dissociated cells are plated on glass coverslips to establish motor cortex cultures in vitro 32

For the fastest and most effective absorption spray it inside of the cheek or under the tongue and hold a few seconds before swallowing

Hydrogen Water Provides Faster Cellular Protection While plant-based antioxidants work through digestion and metabolism, hydrogen water is absorbed immediately, providing instant oxidative stress relief at the cellular level