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3 Why the FDAs RTCT Move Matters Early-phase trials are a particular bottleneck in drug development, marked by high uncertainty and small patient populations, with data flowing from sites to sponsors and only then to the FDA

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This interpretation is supported by our in vivo results showing that Il24 / mice developed less airway fibrosis and mucus accumulation compared to WT controls, in both OVA- and HDM-induced asthma models