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Experimental studies and genome-wide association studies (GWAS) have identified a number of genes and their protein products that serve as UA transporters in the kidney: SLC22A12 [UA transporter (URAT1)], SLC2A9 (GLUT9), ABCG2 [ATP-binding cassette subfamily 2 also known as breast cancer resistance protein (BCRP)], SLC22A6 [organic anion transporter (OAT1)], SLC22A7 (OAT2), SLC22A8 (OAT3), SLC22A11 (OAT4), SLC22A13 (OAT10), SLC17A1 [Na + /phosphate transporter (NPT1)], SLC17A3 (NPT4), ABCC4 [multidrug resistance protein 4 (MRP4)] and PDZK1 (PZK domain containing 1 protein)

is a consultant for Evrys Bio and co-founder of Galilei BioSciences

Wang Z, Ju Y, Ali Z, Yin H, Sheng F, Lin J, et al

Consequently, it is plausible that iron accumulation in RTECs may aggravate inflammatory responses by increasing ROS production, ultimately resulting in renal failure

Methylcobalamin injections are suitable for: Individuals diagnosed with Vitamin B-12 deficiency