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Enrolled participants (n = 246) underwent a 14-week induction period with different subcutaneous doses (50 mg, 150 mg, and 450 mg every four weeks), followed by a 56-week follow-up period

Subgroup analysis suggested benefits for patients under 60 years old, highlighting the importance of precision medicine

doi: 10.2337/diabetes.54.3.679

Chronic tissue safety: Repeated penetration of gastrointestinal tissue raises unresolved questions regarding cumulative injury, ulceration, scarring, bleeding risk, or tissue remodeling