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In the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced in vivo model of Parkinsons disease, activated microglia were found to express Shh, and most neural cells, except oligodendrocytes, responded to microglia-derived Shh in MPTP-treated substantia nigra [42]

GLP-1 receptor agonists trigger nausea through activation of central GLP-1 receptors in the brainstem, specifically in the area postrema and the nucleus of the solitary tract

If you normally inject on Monday and then inject on Thursday one week and Sunday the next, you are creating unnecessary fluctuation in blood levels

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Novotny, 2008