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In June 2025, the Medicines and Healthcare products Regulatory Agency (MHRA) called on healthcare professionals to submit Yellow Card reports on behalf of patients who develop acute pancreatitis while using GLP-1 receptor agonists

The reason is that slowed gastric emptying can reduce contraceptive absorption, particularly during dose changes

Conversely, fewer studies have investigated the role of SGLT-2is on GH/IGF-1

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Underactive sebaceous glands result in dry skin, while overactivity leads to oily skin, where inflammations and bacteria can proliferate, causing itching and further issues