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For patients with known asymptomatic gallstones who are about to start high-dose GLP-1 therapy, the balance is different and pre-emptive surgery may be reasonable

The drugs are already being investigated as treatments for certain muscle- or bone-related conditions, but Regeneron reasoned that they could also be used to proactively prevent muscle loss while taking a GLP-1

They will assess whether the benefits of continuing the medication outweigh the discomfort of the side effects

Many patients reduce to half their peak dose once they reach stable weight

These medications target the GLP-1 receptor pathway, which helps control appetite and encourage sustainable weight loss