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Semaglutide does not directly affect intrinsic factor production, but the reduced stomach acid environment can compromise the initial separation step that makes b12 available for intrinsic factor binding
Even those who get enough in their diet can be deficient in the vitamin if they have certain medical conditions or take specific medications
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Options include partial reconstitution (if feasible with your vial format), freezing portions of reconstituted solution (accepting some potency loss), or adjusting your dose higher to use everything before expiration
For areas with weaker blood flow, such as the frontal hairline and vertex, this improved environment helps prevent follicular degradation caused by poor nutrient supply
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