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doi: 10.1007/s13311-017-0600-5 147 EspositoPChandlerNKandereKBasuSJacobsonSConnollyRet al

Rather than mimicking gut hormones, phentermine stimulates the sympathetic nervous system the body's "fight or flight" response in a targeted way that suppresses appetite

Exclusion criteria The presence of serious somatic disorders, substance abuse except for cigarettes and caffeine, and history of high mood (mania or hypomania), mental dysfunction, dementia, acute psychiatric disorders according to the psychiatrist, and medication that causes depression in the patient were excluded from the study

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Interestingly, GLP-1RA drugs act on receptors that are expressed in brain areas involved in impulse control, reward and addiction potentially explaining their effectiveness in curbing appetite and addiction disorders, said Al-Aly, the director of the Clinical Epidemiology Center at the VA St