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I think the big problems is that up until recently, and I don't know if you've seen some of the new kind of microbiome tests that have come out by Dr

They have realistic expectations about the side effect profile and are willing to tolerate gastrointestinal discomfort in the early weeks

This decline leads to health problems like cognitive issues and metabolic disorders, which makes people think about ways to keep their NAD+ at good levels

Rigorous human pharmacokinetic data do not exist because no completed Phase 1-3 clinical trials have been published

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