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Patients with Pernicious Anaemia, and their families, were unable to reconcile this latest advice with the information that they were given at diagnosis that their treatment would be a life-saving injection every month, every two months or at the least every three months

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After 1.5 g of residue was dissolved in 10 mL of methanol, 0.15 mL of hydrazine monohydrate was added, and this mixture was refluxed at 80C for 1 h