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Human cytochromes P4501A1 and P4501A2: R -warfarin metabolism as a probe

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For the generation of the chimeric E1 (ChE1) gene, the gene encoding E1 (41-957) was fused to the 5-terminus of the gene encoding Sae2 (450-549), and the A680T, N728Y, F729I, A788S, D853E, and T898S mutations were generated by PCR 54

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Mitochondrial superoxide regulates nuclear envelope integrity and ageing via redox-mediated lipid metabolism