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In drug design, although both can increase the hydrophilicity of molecules, the single primary amino group provided by lysine is more amenable to chemical modification and derivatization than the guanidinium group of arginine

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"Now, basically, everyone's coming to the middle and asking, 'How do we responsibly cover these drugs?'" Part of responsible coverage, Inkinen said, is providing other forms of support to patients who stop using GLP-1 medications, by choice or otherwise