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By fitting the plasma concentrations to a non-compartmental PK model 34 , we found that the IgG1-REW variants were present at higher concentrations in plasma over time (AUC) compared to WT, had slower clearance, longer mean residence time and lower volume of distribution at steady state (Table S4)

Trautmann ME, Han J, Ruggles J

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The Asia Pacific data show no significant difference in the age of presentation between AIH types 1 and 2