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Mittler et al., 2022) that can cause damage such as lipid degradation, protein degradation, nucleic acid damage, and induce programmed cell death (PCD) (Das and Roychoudhury, 2014)

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DTNB and GSH react to generate 5-Mercapto-2-nitrobenzoic acid (TNB) in Fig

At the same time, real-life exposure is inherently mixed and involves complex particle mixtures and co-exposures, and many experimental studies (across polymer types) still rely on well-defined laboratory particles rather than environmentally aged, heterogeneous materials, which should be considered when interpreting environmental relevance